Publications-Physiology Faculty

January -  December 2016


Steve E. Cala, Ph.D.

  1. Wu AZ, Xu D, Yang N, Lin SF, Chen PS, Cala SE, Chen Z  Phospholamban is concentrated in the nuclear envelope of cardiomyocytes and involved in perinuclear/nuclear calcium handling. J Mol Cell Cardiol. 2016 Sep 15. pii: S0022-2828(16)30357-1. PMID: 27642167

Xuequn Chen, Ph.D.

  1. Zheng Z, Kim H, Qiu Y, Chen X, Mendez R, Dandekar A, Zhang X, Zhang C, Liu AC, Yin L, Lin JD, Walker PD, Kapatos G, Zhang K. CREBH Couples Circadian Clock with Hepatic Lipid Metabolism. Diabetes. 2016 Aug 9. pii: db160298. [PMID: 27507854
  2. Wang H, Tri Anggraini F, Chen X, DeGracia DJ. Embryonic lethal abnormal vision proteins and adenine and uridine-rich element mRNAs after global cerebral ischemia and reperfusion in the rat. J Cereb Blood Flow Metab. 2016 Jul 5. pii: 0271678X16657572. PMID: 27381823
  3. Feng HZ, Chen X, Malek M, Jin JP. Slow recovery of fatigue resistance in mouse soleus muscle corresponding to decreased mitochondrial function and a compensatory increase in type I slow fibers. Am J Physiol Cell Physiol. 2016 Jan 1;310(1):C27-40. Epub 2015 Oct 7. PMID: 26447205

Charles S. Chung, Ph.D.

  1. Blair CA, Haynes P, Campbell SG, Chung C, Mitov MI, Dennis D, Bonnell MR, Hoopes CW, Guglin M, Campbell KS. A Protocol for Collecting Human Cardiac Tissue for Research. VAD J. 2016;2(1). doi: 10.13023/VAD.2016.12. PMID: 28042604
  2. Chung CS, Afonso L. Heart Rate Is an Important Consideration for Cardiac Imaging of Diastolic Function. JACC Cardiovasc Imaging. 2016 Feb 10. pii: S1936-878X(15)01005-0. PMID: 26897673

Steve E. DiCarlo, Ph.D.

  1. Lujan HL, DiCarlo SE. Alterations in Cardiac Electrophysiology after Spinal Cord Injury and Implications for Exercise.  In, The Physiology of Exercise in Spinal Cord Injury; Physiology in Health and Disease, J. A. Taylor (ed.) ISBN 978-1-4939-6662-2© The American Physiological Society 2016
  2. Lujan HL, DiCarlo SE. Shock and awe pedagogy! Adv Physiol Educ. 2016 Dec;40(4):467-468. PMID: 27697963
  3. Augustyniak RA, Ables AZ, Guilford P, Lujan HL, Cortright RN, DiCarlo SE. Intrinsic motivation: an overlooked component for student success. Adv Physiol Educ. 2016 Dec;40(4):465-466. PMID: 27697962
  4. Lujan HL, DiCarlo SE. Humor promotes learning! Adv Physiol Educ. 2016 Dec;40(4):433-434. NPMID: 27697955
  5. Kurtz, TW, DiCarlo, SE and Morris RC:  Logical Issues with the Pressure Natriuresis Theory of Chronic Hypertension Am J Hypertens (2016) 29 (12):1325-1331.
  6. Lujan HL, Rivers JP, DiCarlo SE. Complex and interacting influences of the autonomic nervous system on cardiac electrophysiology in conscious mice. Auton Neurosci. 2016 Aug 29. pii: S1566-0702(16)30155-2. PMID: 27594686
  7. Kurtz TW, DiCarlo SE, Pravenec M, Schmidlin O, Tanaka M, Morris RC Jr.  An alternative hypothesis to the widely held view that renal excretion of sodium accounts for resistance to salt-induced hypertension. Kidney Int. 2016 Aug 18. pii: S0085-2538(16)30310-6. PMID: 27546606

Bhanu P. Jena, Ph.D.

  1. Naik AR, Kulkarni SP, Lewis KT, Taatjes DJ, Jena BP. (2016) Functional reconstitution of the insulin-secreting porosome complex in live cells.  Endocrinology. 157:54-60. PMID: 26523491
  2. Naik AR, Lewis KT, Jena BP. (2015) The Neuronal Porosome Complex in Health and Disease.  Exp. Biol. Med. (Maywood) 241(2):115-130
  3. Najy A, Dyson G, Jena BP, Lin C-Y, Kim H-R. (2016) Matriptase Activation and Shedding through PDGF-D mediated Extracellular Acidosis.  Am J. Physiol Cell Physiol 10(4):C293-304. PMID: 26157007
  4. Li M, Deguchi T, Näreoja T, Jena BP, Hänninen P, Larsson L. (2015) Nanometric features of myosin filaments extracted from a single muscle fiber to uncover the mechanisms underlying organized motility. Arch Biochem Biophys. Jun 23. pii: S0003-9861(15)00274-X. PMID: 26116379

J.P. Jin, M.D., Ph.D.

  1. Feng HZ, Jin JP. Carbonic Anhydrase III Is Expressed in Mouse Skeletal Muscles Independent of Fiber Type-Specific Myofilament Protein Isoforms and Plays a Role in Fatigue Resistance.Front Physiol. 2016 Dec 15;7:597. doi: 10.3389/fphys.2016.00597. PMID: 28018233
  2. Hossain MM, Zhao G, Woo MS, Wang JH, Jin JP. Deletion of calponin 2 in mouse fibroblasts increases myosin II-dependent cell traction force. Biochemistry.  2016 Oct 13. PMID: 27733037
  3. Sheng JJ, Feng HZ, Pinto JR, Wei H, Jin JP. Increases of desmin and α-actinin in mouse cardiac myofibrils as a response to diastolic dysfunction. J Mol Cell Cardiol. 2016 Oct;99:218-229. doi: 10.1016/j.yjmcc.2015.10.035. PMID: 26529187
  4. Mondal A, Jin JP. Protein Structure-Function Relationship at Work: Learning from Myopathy Mutations of the Slow Skeletal Muscle Isoform of Troponin T. Front Physiol. 2016 Oct 13;7:449. PMID: 27790152
  5. Usacheva EA, Jin JP, Peterson LR. Host response to Clostridium difficile infection: Diagnostics and detection. J Glob Antimicrob Resist. 2016 Sep 20;7:93-101. doi: 10.1016/j.jgar.2016.08.002. PMID: 27693863
  6. Liu R, Jin JP. Deletion of calponin 2 in macrophages alters cytoskeleton-based functions and attenuates the development of atherosclerosis. J Mol Cell Cardiol. 2016 Aug 26. pii: S0022-2828(16)30319-4. doi: 10.1016/j.yjmcc.2016.08.019. PMID: 27575021
  7. Huang QQ, Hossain MM, Sun W, Xing L, Pope RM, Jin JP. Deletion of calponin 2 in macrophages attenuates the severity of inflammatory arthritis in mice. Am J Physiol Cell Physiol. 2016 Aug 3:ajpcell.00331.2015. PMID: 27488671
  8. Amarasinghe CK, Hossain MM, Jin JP. Functional basis of three new recessive mutations of slow skeletal muscle troponin T found in non-Amish TNNT1 nemaline myopathies. Biochemistry. 2016 Jul 18. PMID: 27429059
  9. Liu R, Jin JP. Calponin isoforms CNN1, CNN2 and CNN3: Regulators for actin cytoskeleton functions in smooth muscle and non-muscle cells. Gene. 2016 Mar 10. PMID: 26970176
  10. Zhang T, Pereyra AS, Wang ZM, Birbrair A, Reisz JA, Files DC, Purcell L, Feng X, Messi ML, Feng H, Chalovich J, Jin JP, Furdui C, Delbono O. Calpain inhibition rescues troponin T3 fragmentation, increases Cav1.1, and enhances skeletal muscle force in aging sedentary mice. Aging Cell. 2016 Feb 19. PMID: 26892246
  11. Gunther LK, Feng HZ, Wei H, Raupp J, Jin JP, Sakamoto T. Effect of N-terminal extension of cardiac troponin I on the Ca2+ regulation of ATP-binding and ADP dissociation of myosin II in native cardiac myofibrils. Biochemistry. 2016 Mar 29;55(12):1887-97. doi: 10.1021/acs.biochem.5b01059. Epub 2016 Mar 14. PMID: 26862665
  12. Jin JP. Evolution, Regulation, and Function of N-terminal Variable Region of Troponin T: Modulation of Muscle Contractility and Beyond. Int Rev Cell Mol Biol. 2016;321:1-28. PMID: 26811285
  13. Wei B, Jin JP. TNNT1, TNNT2, and TNNT3: Isoform genes, regulation, and structure-function relationships. Gene. 2016 Jan 13. pii: S0378-1119(16)00037-8. PMID: 26774798
  14. Sheng JJ, Jin JP. TNNI1, TNNI2 and TNNI3: Evolution, regulation, and protein structure-function relationships. Gene. 2016 Jan 15;576(1 Pt 3):385-94. doi: 10.1016/j.gene.2015.10.052. Epub 2015 Oct 23. Review. PMID: 26526134
  15. Feng HZ, Chen X, Malek M, Jin JP. Slow recovery of fatigue resistance in mouse soleus muscle corresponding to decreased mitochondrial function and a compensatory increase in type I slow fibers. Am J Physiol Cell Physiol. 2016 Jan 1;310(1):C27-40. Epub 2015 Oct 7. PMID: 26447205

Robert D. Lasley, PhD

  1. Haque MZ, McIntosh VJ, Abou Samra AB, Mohammad RM, Lasley RD. Cholesterol Depletion Alters Cardiomyocyte Subcellular Signaling and Increases Contractility. PLoS One. 2016 Jul 21;11(7):e0154151. PMID: 27441649

Jason H. Mateika, PhD

  1. Wains SA, El-Chami M, Lin HS, Mateika JH. Impact of arousal threshold and respiratory effort on the duration of breathing events across sleep stage and time of night. Respir Physiol Neurobiol. 2016 Dec 28;237:35-41. doi: 10.1016/j.resp.2016.12.009. [Epub ahead of print] PMID: 28040523
  2. Lozo T, Komnenov D, Badr MS, Mateika JH. Sex differences in sleep disordered breathing in adults. Respir Physiol Neurobiol. 2016 Nov 9. pii: S1569-9048(16)30222-1. doi: 10.1016/j.resp.2016.11.001. [Epub ahead of print] Review. PMID: 27836648
  3. Komnenov D, Solarewicz JZ, Afzal F, Nantwi KD, Kuhn DM, Mateika JH. Intermittent hypoxia promotes recovery of respiratory motor function in spinal cord injured mice depleted of serotonin in the central nervous system. J Appl Physiol (1985). 2016 Jul 8:jap.00448.2016. PMID: 27402561
  4. Mateika JH, Komnenov D. Intermittent hypoxia initiated plasticity in humans: A multipronged therapeutic approach to treat sleep apnea and overlapping co-morbidities. Exp Neurol. 2016 May 8. pii: S0014-4886(16)30121-2. PMID: 27170208

Patrick J. Mueller, PhD

  1. Subramanian M, Mueller PJ. Altered Differential Control of Sympathetic Outflow Following Sedentary Conditions: Role of Subregional Neuroplasticity in the RVLM. Front Physiol. 2016 Jul 19;7:290. PMID: 27486405
  2. Wang H, Case AJ, Wang WZ, Mueller PJ, Smith SA. Redox Signaling and Neural Control of Cardiovascular Function. Oxid Med Cell Longev. 2016;2016:7086018. doi: 10.1155/2016/7086018. PMID: 27123156

Donal S. O’Leary, PhD

  1. Kaur J, Alvarez A, Hanna HW, Krishnan AC, Senador D, Machado TM, Altamimi YH, Lovelace AT, Dombrowski MD, Spranger MD, O'Leary DS. Interaction between the muscle metaboreflex and the arterial baroreflex in control of arterial pressure and skeletal muscle blood flow. Am J Physiol Heart Circ Physiol. 2016 Nov 1;311(5):H1268-H1276. doi: 10.1152/ajpheart.00501.2016. PMID: 27614226
  2. Spranger MD, Kaur J, Sala-Mercado JA, Krishnan AC, Abu-Hamdah R, Alvarez A, Machado TM, Augustyniak RA, O'Leary DS. Exaggerated coronary vasoconstriction limits muscle metaboreflex-induced increases in ventricular performance in hypertension. Am J Physiol Heart Circ Physiol. 2016 Oct 21:ajpheart.00417.2016. PMID: 27769997
  3. Ardell JL, Andresen MC, Armour JA, Billman GE, Chen PS, Foreman RD, Herring N, O'Leary DS, Sabbah HN, Schultz HD, Sunagawa K, Zucker IH. Translational Neurocardiology: preclinical models and cardioneural integrative aspects. J Physiol. 2016 Apr 21. doi: 10.1113/JP271869. PMID: 27098459
  4. Spranger MD, Krishnan AC, Levy PD, O'Leary DS, Smith SA. Reply to "Letter to the editor: Applying the blood flow restriction pressure: the elephant in the room". Am J Physiol Heart Circ Physiol. 2016 Jan PMID: 26724282

Karin Przyklenk, PhD

  1. Pearson C, Przyklenk K, Mika VH, Ayaz SI, Ellis M, Varade P, Tolomello R, Welch RD. Utility of point of care assessment of platelet reactivity (using the PFA-100®) to aid in diagnosis of stroke. Am J Emerg Med. 2016 Nov 15. pii: S0735-6757(16)30864-6. doi: 10.1016/j.ajem.2016.11.036. [Epub ahead of print] PMID: 27955971
  2. Hausenloy DJ, Barrabes JA, Bøtker HE, Davidson SM, Di Lisa F, Downey J, Engstrom T, Ferdinandy P, Carbrera-Fuentes HA, Heusch G, Ibanez B, Iliodromitis EK, Inserte J, Jennings R, Kalia N, Kharbanda R, Lecour S, Marber M, Miura T, Ovize M, Perez-Pinzon MA, Piper HM, Przyklenk K, Schmidt MR, Redington A, Ruiz-Meana M, Vilahur G, Vinten-Johansen J, Yellon DM, Garcia-Dorado D. Ischaemic conditioning and targeting reperfusion injury: a 30 year voyage of discovery. Basic Res Cardiol. 2016 Nov;111(6):70. PMID: 27766474
  3. Dong Y, Undyala VV, Przyklenk K. Inhibition of mitochondrial fission as a molecular target for cardioprotection: critical importance of the timing of treatment. Basic Res Cardiol. 2016 Sep;111(5):59. doi: 10.1007/s00395-016-0578-x. PMID: 27573530
  4. Kumar R, Bukowski MJ, Wider JM, Reynolds CA, Calo L, Lepore B, Tousignant R, Jones M, Przyklenk K, Sanderson TH. Mitochondrial dynamics following global cerebral ischemia. Mol Cell Neurosci. 2016 Aug 25;76:68-75. PMID: 27567688
  5. Garratt KN, Whittaker P, Przyklenk K. Remote Ischemic Conditioning and the Long Road to Clinical Translation: Lessons Learned From ERICCA and RIPHeart. Circ Res. 2016 Apr 1;118(7):1052-4. doi: 10.1161/CIRCRESAHA.115.308102. PMID: 27034272
  6. Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition). In Autophagy 12(1) 2016 (Taylor & Francis,)
  7. Gremmel T, Yanachkov IB, Yanachkova MI, Wright GE, Wider J, Undyala VV, Michelson AD, Frelinger AL 3rd, Przyklenk K. Synergistic Inhibition of Both P2Y1 and P2Y12 Adenosine Diphosphate Receptors As Novel Approach to Rapidly Attenuate Platelet-Mediated Thrombosis. Arterioscler Thromb Vasc Biol. 2016 Jan 7. PMID: 26743169

Jeff L. Ram, PhD

  1. Kato I, Vasquez AA, Moyerbrailean G, Land S, Sun J, Lin HS, Ram JL. Oral microbiome and history of smoking and colorectal cancer. J Epidemiol Res. 2016 Oct;2(2):92-101. doi: 10.5430/jer.v2n2p92. PMID: 28111632
  2. Vasquez AA, Hudson PL, Fujimoto M, Keeler K, Armenio PM, Ram JL. Eurytemora carolleeae in the Laurentian Great Lakes revealed by phylogenetic and morphological analysis. Journal of Great Lakes Research. Ref: GLR-D-15-00172R1 (accepted)
  3. Kato I, Vasquez AA, Moyerbrailean G, Land S, Sun J, Lin HS, Ram JL. Oral microbiome and history of smoking and colorectal cancer. Journal of Epidemiological Research. J Epidemiol Res. 2016 Oct;2(2):92-101. doi: 10.5430/jer.v2n2p92. PMID: 28111632
  4. Failla AJ, Vasquez AA, Hudson P, Fujimoto M, Ram JL. Morphological identification and COI barcodes of adult flies help determine species identities of chironomid larvae (Diptera, Chironomidae). Bull Entomol Res. 2016 Feb;106(1):34-46. doi: 10.1017/S0007485315000486. PMID: 26072670

James A. Rillema, PhD

  1. Ikonomov OC, Sbrissa D, Delvecchio K, A Rillema J, Shisheva A. Unexpected severe consequences of Pikfyve deletion by aP2- or Aq-promoter-driven Cre expression for glucose homeostasis and mammary gland development. Physiol Rep. 2016 Jun;4(11). PMID: 27273882

Assia Shisheva, PhD

  1. Tisdale EJ, Talati NK, Artalejo CR, Shisheva A. GAPDH Binds Akt to Facilitate Cargo Transport in The Early Secretory Pathway. Exp Cell Res. 2016 Nov 3. pii: S0014-4827(16)30361-5. doi: 10.1016/j.yexcr.2016.10.025. [Epub ahead of print] PMID: 27818247
  2. Compton LM, Ikonomov OC, Sbrissa D, Garg P, Shisheva A. Active vacuolar H+ATPase and functional cycle of Rab5 are required for the vacuolation defect triggered by PtdIns(3,5)P2 loss under PIKfyve or Vps34 deficiency. Am J Physiol Cell Physiol. 2016 Jun 22:ajpcell.00104.2016. PMID: 27335171
  3. Ikonomov OC, Sbrissa D, Delvecchio KA, Rillema J, Shisheva A. Unexpected severe consequences of Pikfyve deletion by aP2- or Aq-promoter-driven Cre expression for glucose homeostasis and mammary gland development. Physiol Rep. 2016 Jun;4(11). pii: e12812. doi: 10.14814/phy2.12812. PMID: 27273882
  4. Venkatareddy M, Verma R, Kalinowski A, Patel SR, Shisheva A, Garg P. Distinct Requirements for Vacuolar Protein Sorting 34 Downstream Effector Phosphatidylinositol 3-Phosphate 5-Kinase in Podocytes Versus Proximal Tubular Cells. J Am Soc Nephrol. 2016 Jan 29. pii: ASN.2015050555. PMID: 26825532

Fei Sun, PhD

  1. Dandekar A, Qiu Y, Kim H, Wang J, Hou X, Zhang X, Zheng Z, Mendez R, Yu FS, Kumar A, Fang D, Sun F, Zhang K. TLR signaling interacts with CREBH to modulate HDL in response to bacterial endotoxin. J Biol Chem. 2016 Sep 16. pii: jbc.M116.755728. PMID: 27637329
  2. Guan X, Hou Y, Sun F, Yang Z, Li C. Dysregulated Chemokine Signaling in Cystic Fibrosis Lung Disease: A Potential Therapeutic Target. Curr Drug Targets. 2016;17(13):1535-44. PMID: 26648071
  3. Zaman K, Sawczak V, Zaidi A, Butler M, Bennett D, Getsy P, Zeinomar M, Greenberg Z, Forbes M, Rehman S, Jyothikumar V, DeRonde K, Sattar A, Smith L, Corey D, Straub A, Sun F, Palmer L, Periasamy A, Randell S, Kelley TJ, Lewis SJ, Gaston B. Augmentation of CFTR maturation by S-nitrosoglutathione reductase. Am J Physiol Lung Cell Mol Physiol. 2016 Feb 1;310(3):L263-70. PMID: 26637637

Douglas R. Yingst, Ph.D.

  1. Massey KJ, Li Q, Rossi NF, Keezer SM, Mattingly RR, Yingst DR. Phosphorylation of Rat Kidney Na, K-pump at Ser-938 Required for Rapid Angiotensin II-dependent Stimulation of Activity and Trafficking in Proximal Tubule Cells. Am J Physiol Cell Physiol. 2016 Feb 1;310(3):C227-32. PMID: 26582472