Kenneth Lewis

Kenneth Lewis

Kenneth Lewis

Position Title

Post doctoral fellow at the University of Michigan

Publications

  1. Naik AR, Kuhn ER, Lewis KT, Kokotovich KM, Maddipati KR, Chen X, Hörber JHK, Taatjes DJ, Potoff J, Jena BP. Self-Assembly and Biogenesis of Cellular Membrane is Dictated by Membrane Stretch and Composition. J Phys Chem B. 2019 Jul 19. doi: 10.1021/acs.jpcb.9b04769. PMID: 31322890
  2. Naik, A. R., Pernal, S., Lewis, K. T., Wu, Y., Wu, H., Carruthers, N. J., Stemmer, P. M., Jena, B. P. (2019) Human skeletal muscle cells on engineered 3D platform express key growth and developmental proteins. ACS Biomaterials Science & Engineering DOI: 10.1021/acsbiomaterials.8b01338
  3. Li Z, Hardij J, Evers SS, Hutch CR, Choi SM, Shao Y, Learman BS, Lewis KT, Schill RL, Mori H, Bagchi DP, Romanelli SM, Kim KS, Bowers E, Griffin C, Seeley RJ, Singer K, Sandoval DA, Rosen CJ, MacDougald OA. G-CSF partially mediates effects of sleeve gastrectomy on the bone marrow niche. J Clin Invest. 2019 May 6;130. pii: 126173. doi: 10.1172/JCI126173. eCollection 2019 May 6. PMID: 31063988
  4. Lewis KT, Bullock JR, Drumright RT, Olsen MJ, Penman AD. Changes in peripapillary blood vessel density in Graves' orbitopathy after orbital decompression surgery as measured by optical coherence tomography angiography. Orbit. 2019 Apr;38(2):87-94. doi: 10.1080/01676830.2018.1446539. PMID: 29517388
  5. Lewis KT, MacDougald OA. Bone: Bone marrow adipocytes in 3D. Nat Rev Endocrinol. 2018 May;14(5):254-255. doi: 10.1038/nrendo.2018.31. Epub 2018 Mar 16. PMID: 29546873
  6. Lewis KT, Naik AR, Laha SS, Wang S, Mao G, Kuhn E, Jena BP. Secretion induces cell pH dynamics impacting assembly-disassembly of the fusion protein complex: A combined fluorescence and atomic force microscopy study. Semin Cell Dev Biol. 2018 Jan;73:57-63. doi: 10.1016/j.semcdb.2017.08.003. Epub 2017 Aug 3. Review. PMID: 28779980
  7. Jena BP, Stemmer PM, Wang S, Mao G, Lewis KT, Walz DA (2017). Human platelet vesicles exhibit distinct size and proteome. J Proteome Res. 2017 Jul 7;16(7):2333-2338. doi: 10.1021/acs.jproteome.7b00309. PMID: 28587468
  8. Lewis KT, Maddipati KR, Naik AR, Jena BP. (2017). Unique lipid chemistry of synaptic vesicle and synaptosome membrane revealed using mass spectrometry. ACS Chemical Neuroscience. ACS Chem Neurosci. 2017 Jun 21;8(6):1163-1169, doi: 10.1021/acschemneuro.7b00030. PMID: 28244738
  9. Arachchige MP, Laha SS, Naik AR, Lewis KT, Naik R, Jena, BP.(2016) Functionalized nanoparticles enable tracking the rapid entry and release of doxorubicin in human pancreatic cancer cells. Micron. 2017 Jan;92:25-31. doi: 10.1016/j.micron.2016.10.005. PMID: 27846432
  10. Naik AR, Kulkarni SP, Lewis KT, Taatjes DJ, Jena BP. Functional reconstitution of the insulin-secreting porosome complex in live cells. Endocrinology. 2016 Jan;157(1):54-60. PMID: 26523491
  11. Naik AR, Lewis KT, Jena BP. The Neuronal Porosome Complex in Health and Disease. Exp Biol Med (Maywood). 2016 Jan;241(2):115-30. doi: 10.1177/1535370215598400. Epub 2015 Aug 11. Review. PMID: 26264442
  12. Rajagopal A, Kulkarni S, Lewis KT, Chen X, Maarouf A, Kelly CV, Taatjes DJ, Jena BP. Proteome of the insulin-secreting Min6 cell porosome complex: Involvement of Hsp90 in its assembly and function. J Proteomics. 2014 Nov 20;114C:83-92. PMID: 25464371
  13. Lewis KT, Maddipati KR, Taatjes DJ, Jena BP. Neuronal porosome lipidome. J Cell Mol Med. 2014 Sep 16. PMID: 25224862
  14. Hou X, Lewis KT, Wu Q, Wang S, Chen X, Flack A, Mao G, Taatjes DJ, Sun F, Jena BP. Proteome of the porosome complex in human airway epithelia: interaction with the cystic fibrosis transmembrane conductance regulator (CFTR). J Proteomics. 2014 Jan 16;96:82-91. PMID: 24220302
  15. Kovari, L.C., Brunzelle, J.S., Lewis, KT, Cho, W.J., Lee, J-S., Taatjes, D.J., Jena, B.P. (2013) X-ray solution structure of the native neuronal porosome-synaptic vesicle complex: Implication in neurotransmitter release. Micron. 2014 Jan;56:37-43. PMID: 24176623
  16. Shah C1, Antonucci JV, Wilkinson JB, Wallace M, Ghilezan M, Chen P, Lewis K, Mitchell C, Vicini F. (2011) Twelve-year clinical outcomes and patterns of failure with accelerated partial breast irradiation versus whole-breast irradiation: results of a matched-pair analysis. Radiotherapy and Oncology, 100: pp. 210–214

Awards & Honors

  • Marion I. Barnhart Graduate Student Award (2014)
  • Elected Graduate Student Representative (2014-2015)

 

Education

2012 - B.S. in Biology, Oakland University

2018 - Ph.D. in Physiology, Wayne State University

Mentor

Bhanu Jena, Ph.D.

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