Jennifer Condon, Ph.D.
Office address
C.S. Mott Center
275 E. Hancock
Position
Associate Professor - Obstetrics and Gynecology; Reproductive Sciences Concentration RepresentativeResearch
The Condon laboratory focuses on defining the molecular mechanisms that regulate gestational length in order to understand the processes that lead to the onset of term and preterm birth. The success of a pregnancy is in part dependent upon the capacity of the pregnant uterine myocyte to maintain a quiescence phenotype despite being exposed to potential uterotonic, intrinsic and extrinsic stimuli across gestation. For an appropriate gestational length to be achieved the pregnant uterine myocyte must detect, tolerate and adapt to pregnancy-associated uterotonic provocations. The Condon lab examines the capacity of the uterine myocyte endoplasmic reticulum stress response to detect potential uterotonic events and generate a tocolytic signaling cascade to accommodate quiescence during these transitional episodes. Our preliminary data suggests that the uterine myocyte endoplasmic reticulum stress response and its related unfolded protein response regulate uterine contractile potential during pregnancy in a caspase 3, dependent manner.
Publications
For a complete list of publications, please visit Condon PubMed
Post graduate training
- 1999-2000 Post Doctoral Fellow-University of Texas Southwestern Medical Center, Department of Obstetrics & Gynecology
- 2000-2004 Post Doctoral Fellow-University of Texas Southwestern Medical Center, Department of Biochemistry
Education
- 1994-B.S. Molecular Genetics, University College, Dublin, Ireland
- 1999-Ph.D. Molecular Endocrinology, University of Birmingham, United Kindom