Maryam Safdar

Maryam Safdar

Maryam Safdar

Position Title

 Ph.D. Candidate

Joint Appointments

 MD/PhD program

Areas of Interest

Endurance exercise as a rescue for negative health outcomes resulting from circadian rhythm disturbances in Drosophila 

Narrative Bio


  1. Safdar M, Wessells R. Octopamine Rescues Endurance and Climbing Speed in Drosophila Clkout Mutants with Circadian Rhythm Disruption. Cells 2023, 12(21), 2515;
  2. Cobb T, Hwang I, Soukar M, Namkoong S, Cho US, Safdar M, Kim M, Wessells RJ, Jun Hee Lee JH. Iditarod, a Drosophila homolog of the Irisin precursor FNDC5, is critical for exercise performance and cardiac autophagy. Proc Natl Acad Sci. 2023 Sep 26;120(39):e2220556120. doi: 10.1073/pnas.2220556120.
  3. Ahmed S, Safdar M, Morton C, Soave N, Patel R, Castillo K, Lalande S, Jimenez L, Mateika JH, Wessells R. Effect of virtual reality-simulated exercise on sympathovagal balance. PLoS One. 2020 Jul 16;15(7):e0235792. doi: 10.1371/journal.pone.0235792. PMID: 32673347
  4. Sujkowski A, Spierer AN, Rajagopalan T, Bazzell B, Safdar M, Imsirovic D, Arking R, Rand DM, Wessells R. Mito-nuclear interactions modify Drosophila exercise performance. Mitochondrion. 2019 Jul;47:188-205. doi: 10.1016/j.mito.2018.11.005. PMID: 30408593


 BS in Biology, Wayne State University


Robert Wessells, Ph.D.

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