Maryam Safdar
Position Title
Ph.D. Candidate
Joint Appointments
MD/PhD program
Areas of Interest
Endurance exercise as a rescue for negative health outcomes resulting from circadian rhythm disturbances in Drosophila
Narrative Bio
https://gradprograms.med.wayne.edu/profile/fo3573
Publications
- Safdar M, Wessells R. Octopamine Rescues Endurance and Climbing Speed in Drosophila Clkout Mutants with Circadian Rhythm Disruption. Cells 2023, 12(21), 2515; https://doi.org/10.3390/cells12212515
- Cobb T, Hwang I, Soukar M, Namkoong S, Cho US, Safdar M, Kim M, Wessells RJ, Jun Hee Lee JH. Iditarod, a Drosophila homolog of the Irisin precursor FNDC5, is critical for exercise performance and cardiac autophagy. Proc Natl Acad Sci. 2023 Sep 26;120(39):e2220556120. doi: 10.1073/pnas.2220556120.
- Ahmed S, Safdar M, Morton C, Soave N, Patel R, Castillo K, Lalande S, Jimenez L, Mateika JH, Wessells R. Effect of virtual reality-simulated exercise on sympathovagal balance. PLoS One. 2020 Jul 16;15(7):e0235792. doi: 10.1371/journal.pone.0235792. PMID: 32673347
- Sujkowski A, Spierer AN, Rajagopalan T, Bazzell B, Safdar M, Imsirovic D, Arking R, Rand DM, Wessells R. Mito-nuclear interactions modify Drosophila exercise performance. Mitochondrion. 2019 Jul;47:188-205. doi: 10.1016/j.mito.2018.11.005. PMID: 30408593
Education
BS in Biology, Wayne State University