Alyson Wessells

Alyson Wessells

Alyson Wessells

Position Title

PhD Applicant

Areas of Interest

cardiovascular physiology

Publications

  1. Sujkowski A, Gretzinger A, Soave N, Todi SV, Wessells R. PLoS Genet. Alpha- and beta-adrenergic octopamine receptors in muscle and heart are required for Drosophila exercise adaptations. 020 Jun 24;16(6):e1008778. doi: 10.1371/journal.pgen.1008778. Online ahead of print. PMID: 32579604
  2. *Cobb T, *Sujkowski A, Morton C, Ramesh D, Wessells R. Variation in mobility and exercise adaptations between Drosophila species. J Comp Physiol A Neuroethol Sens Neural Behav Physiol. 2020 Apr 25. doi: 10.1007/s00359-020-01421-x. PMID: 32335730 *These authors contributed equally to this work
  3. Cao T, Sujkowski A, Cobb T, Wessells RJ, Jin JP. The glutamic acid-rich long C-terminal extension of troponin T has a critical role in insect muscle functions. J Biol Chem. 2020 Feb 5. pii: jbc.RA119.012014. doi: 10.1074/jbc.RA119.012014 PMID: 32024695
  4. *Kim M, *Sujkowski A, Namkoong S, Gu B, Cobb T, Kim B, Kowalsky AH, Cho CS, Semple I, Ro SH, Davis C, Brooks SV, Karin M, Wessells RH, Lee JH, Sestrins are evolutionarily conserved mediators of exercise benefits. Nature Communications, 11, Article # 190 (2020), /doi.org/10.1038/s41467-019-13442-5. *These authors contributed equally to this work.
  5. Sujkowski A, Spierer AN, Rajagopalan T, Bazzell B, Safdar M, Imsirovic D, Arking R, Rand DM, Wessells R. Mito-nuclear interactions modify Drosophila exercise performance. Mitochondrion. 2019 Jul;47:188-205. doi: 10.1016/j.mito.2018.11.005. Epub 2018 Nov 6. PMID: 30408593
  6. Sujkowski A, Wessells R. Using Drosophila to Understand Biochemical and Behavioral Responses to Exercise. Exerc Sport Sci Rev. 2018 Apr;46(2):112-120. doi: 10.1249/JES.0000000000000139. Review. PMID: 29346165 Free PMC Article
  7. Sujkowski A, Ramesh D, Brockmann A, Wessells R. Octopamine Drives Endurance Exercise Adaptations in Drosophila. Cell Rep. 2017 Nov 14;21(7):1809-1823. doi: 10.1016/j.celrep.2017.10.065. PMID: 29141215
  8. Laha SS, Naik AR, Kuhn ER, Alvarez M, Sujkowski A, Wessells RJ, Jena BP. Nanothermometry Measure of Muscle Efficiency. Nano Lett. 2017 Feb 8;17(2):1262-1268. doi: 10.1021/acs.nanolett.6b05092. PMID: 28112520
  9. Sujkowski A, Rainier S, Fink JK, Wessells RJ. Delayed Induction of Human NTE (PNPLA6) Rescues Neurodegeneration and Mobility Defects of Drosophila swiss cheese (sws) Mutants. PLoS One. 2015 Dec 15;10(12):e0145356. doi: 10.1371/journal.pone.0145356. eCollection 2015. PMID: 26671664
  10. Dourlen P, Sujkowski A, Wessells R, Mollereau B. Fatty acid transport proteins in disease: New insights from invertebrate models. Prog Lipid Res. 2015 Oct;60:30-40. doi: 10.1016/j.plipres.2015.08.001. Epub 2015 Sep 28. Review. PMID: 26416577
  11. Sujkowski A, Bazzell B, Carpenter K, Arking R, Wessells RJ. Endurance exercise and selective breeding for longevity extend Drosophila healthspan by overlapping mechanisms. Aging (Albany NY). 2015 Aug;7(8):535-52. PMID: 26298685
  12. Laker RC, Xu P, Ryall KA, Sujkowski A, Kenwood BM, Chain KH, Zhang M, Royal MA, Hoehn KL, Driscoll M, Adler PN, Wessells RJ, Saucerman JJ, Yan Z. A novel MitoTimer reporter gene for mitochondrial content, structure, stress, and damage in vivo. J Biol Chem. 2014 Apr 25;289(17):12005-15. doi: 10.1074/jbc.M113.530527. Epub 2014 Mar 18. PMID: 24644293
  13. Sujkowski A, Saunders S, Tinkerhess M, Piazza N, Jennens J, Healy L, Zheng L, Wessells R. dFatp regulates nutrient distribution and long-term physiology in Drosophila. Aging Cell. 2012 Dec;11(6):921-32. doi: 10.1111/j.1474-9726.2012.00864.x. Epub 2012 Aug 27. PMID: 22809097
  14. Tinkerhess MJ, Healy L, Morgan M, Sujkowski A, Matthys E, Zheng L, Wessells RJ. The Drosophila PGC-1α homolog spargel modulates the physiological effects of endurance exercise. PLoS One. 2012;7(2):e31633. doi: 10.1371/journal.pone.0031633. Epub 2012 Feb 13. PMID: 22348115

 

Education

2006 BS in Biology from the University of Toledo

2010 MS in Biology (neuroscience) from the University of Toledo

 

Advisor

Rotating - Dr. Sokol Todi

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