Yi Tian Yap, Ph.D.

Yi Tian Yap, Ph.D.

Yi Tian Yap, Ph.D.

Position Title

Research Scienist @ Sciencell

Areas of Interest

The role of intraflagellar transport in motile cilia: it's trascriptional regulation and trafficking male germ cells

Publications

  1. Yap YT, Li YH, Li W, Banerjee P, Zhang Z. ATP8a1, an IFT27 binding partner, is dispensable for spermatogenesis and male fertility. Mol Reprod Dev. 2021 Apr 6. doi: 10.1002/mrd.23470. PMID: 33821543
  2. Huang Q, Liu Y, Zhang S, Yap YT, Li W, Zhang D, Gardner A, Zhang L, Song S, Hess RA, Zhang Z. Autophagy core protein ATG5 is required for elongating spermatid development, sperm individualization and normal fertility in male mice. Autophagy. 2020 Jul 17:1-15. doi: 10.1080/15548627.2020.1783822. PMID: 32677505
  3. Qu W, Yuan S, Quan C, Huang Q, Zhou Q, Yap Y, Shi L, Zhang D, Guest T, Li W, Yee SP, Zhang L, Cazin C, Hess RA, Ray PF, Kherraf ZE, Zhang Z. The essential role of intraflagellar transport protein IFT81 in male mice spermiogenesis and fertility. Am J Physiol Cell Physiol. 2020 Apr 1. doi: 10.1152/ajpcell.00450.2019. PMID: 32233951
  4. Yuan S, Yap YT, Wood C, Huang Q, Zhang L, Zhang Z, Liu Y. Dissecting the SPAG6 domain that mediates interaction with Snapin. Mol Reprod Dev. 2020 Jan 21. doi: 10.1002/mrd.23318. PMID: 31965676
  5. Wang Z*, Shi Y*, Ma S*, Huang Q*, Yap YT, Shi L, Zhang S, Zhou T, Li W, Hu B, Zhang L, Krawetz SA, Pazour GI, Hess RA, Zhang Z. Abnormal fertility, acrosome formation, IFT20 expression and localization in the conditional Gmap210 knockout mice. AJP-Cell Physiology (in press).

 

Education

2023 Ph.D. in Physiology (Reproductive Sciences Concentration), Wayne State University

2016 B.Sc. Honors (biomedical science) - Unversity of Nottingham, U.K.

Advisor

Dr. Zhibing Zhang

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