Position Title

 PhD Candidate

Joint Appointments

 MD/PhD student

Areas of Interest

The Role of Chronic Placental Inflammation in the Etiology of Preterm Birth and in the Offspring

Publications

1. Garcia-Flores V, Liu Z, Romero R, Pique-Regi R, Xu Y, Miller D, Levenson D, Galaz J, Winters AD, Farias-Jofre M, Panzer JJ, Theis KR, Gomez-Lopez N. Homeostatic Macrophages Prevent Preterm Birth and Improve Neonatal Outcomes by Mitigating In Utero Sterile Inflammation in Mice. J Immunol. 2024 Oct 21:ji2400467. doi: 10.4049/jimmunol.2400467. PMID: 39431882
2. Kanninen T, Tao L, Romero R, Xu Y, Arenas-Hernandez M, Galaz J, Liu Z, Miller D, Levenson D, Greenberg JM, Panzer J, Padron J, Theis KR, Gomez-Lopez N. Thymic stromal lymphopoietin participates in the host response to intra-amniotic inflammation leading to preterm labor and birth. Hum Immunol. 2023 Jul 6:S0198-8859(23)00089-7. doi: 10.1016/j.humimm.2023.06.005. PMID: 37422429
3. Farias-Jofre M, Romero R, Xu Y, Levenson D, Tao L, Kanninen T, Galaz J, Arenas-Hernandez M, Liu Z, Miller D, Bhatti G, Seyerle M, Tarca AL, Gomez-Lopez N. Differential immunophenotype of circulating monocytes from pregnant women in response to viral ligands. BMC Pregnancy Childbirth. 2023 May 6;23(1):323. doi: 10.1186/s12884-023-05562-0. PMID: 37149573
4. Chaiworapongsa T, Romero R, Gotsch F, Gomez-Lopez N, Suksai M, Gallo DM, Jung E, Levenson D, Tarca AL. One-third of patients with eclampsia at term do not have an abnormal angiogenic profile. J Perinat Med. 2022 Dec 27. doi: 10.1515/jpm-2022-0474. PMID: 36567427 Free article.
5. Garcia-Flores V, Romero R, Xu Y, Theis KR, Arenas-Hernandez M, Miller D, Peyvandipour A, Bhatti G, Galaz J, Gershater M, Levenson D, Pusod E, Tao L, Kracht D, Florova V, Leng Y, Motomura K, Para R, Faucett M, Hsu CD, Zhang G, Tarca AL, Pique-Regi R, Gomez-Lopez N. Maternal-fetal immune responses in pregnant women infected with SARS-CoV-2. Nat Commun. 2022 Jan 18;13(1):320. doi: 10.1038/s41467-021-27745-z. PMID: 35042863 Free PMC article.
6. Garcia-Flores V, Romero R, Xu Y, Theis K, Arenas-Hernandez M, Miller D, Peyvandipour A, Galaz J, Levenson D, Bhatti G, Gershater M, Pusod E, Kracht D, Florova V, Leng Y, Tao L, Faucett M, Para R, Hsu CD, Zhang G, Tarca AL, Pique-Regi R, Gomez-Lopez N. Maternal-Fetal Immune Responses in Pregnant Women Infected with SARS-CoV-2. Res Sq. 2021 Mar 31:rs.3.rs-362886. doi: 10.21203/rs.3.rs-362886/v1. Preprint. PMID: 33821263 4
7. Cox A, Schmierer J, D'Angelo J, Smith A, Levenson D, Treanor J, Kim B, Dewhurst S. A Mutated PB1 Residue 319 Synergizes with the PB2 N265S Mutation of the Live Attenuated Influenza Vaccine to Convey Temperature Sensitivity. Viruses. 2020 Oct 31;12(11):1246. doi: 10.3390/v12111246. PMID: 33142846 Free PMC article.
8. Motomura K, Romero R, Tarca AL, Galaz J, Bhatti G, Done B, Arenas-Hernandez M, Levenson D, Slutsky R, Hsu CD, Gomez-Lopez N. Pregnancy-specific transcriptional changes upon endotoxin exposure in mice. J Perinat Med. 2020 Sep 25;48(7):700-722. doi: 10.1515/jpm-2020-0159. PMID: 32866128 Free PMC article.
9. Galaz J, Romero R, Xu Y, Miller D, Levenson D, Para R, Varrey A, Hsu R, Tong A, Hassan SS, Hsu CD, Gomez-Lopez N. Cellular immune responses in amniotic fluid of women with a sonographic short cervix. J Perinat Med. 2020 Sep 25;48(7):665-676. doi: 10.1515/jpm-2020-0037. PMID: 32716907 Free PMC article.
10. Motomura K, Romero R, Xu Y, Theis KR, Galaz J, Winters AD, Slutsky R, Garcia-Flores V, Zou C, Levenson D, Para R, Ahmad MM, Miller D, Hsu CD, Gomez-Lopez N. Intra-Amniotic Infection with Ureaplasma parvum Causes Preterm Birth and Neonatal Mortality That Are Prevented by Treatment with Clarithromycin. mBio. 2020 Jun 23;11(3):e00797-20. doi: 10.1128/mBio.00797-20. PMID: 32576673 Free PMC article.
11. Garcia-Flores V, Romero R, Furcron AE, Levenson D, Galaz J, Zou C, Hassan SS, Hsu CD, Olson D, Metz GAS, Gomez-Lopez N. Prenatal Maternal Stress Causes Preterm Birth and Affects Neonatal Adaptive Immunity in Mice. Front Immunol. 2020 Feb 26;11:254. doi: 10.3389/fimmu.2020.00254. eCollection 2020. PMID: 32174914 Free PMC article.
12. Theis KR, Romero R, Motomura K, Galaz J, Winters AD, Pacora P, Miller D, Slutsky R, Florova V, Levenson D, Para R, Varrey A, Kacerovsky M, Hsu CD, Gomez-Lopez N. Microbial burden and inflammasome activation in amniotic fluid of patients with preterm prelabor rupture of membranes. J Perinat Med. 2020 Feb 25;48(2):115-131. doi: 10.1515/jpm-2019-0398. PMID: 31927525 Free PMC article.
13. Galaz J, Romero R, Xu Y, Miller D, Slutsky R, Levenson D, Hsu CD, Gomez-Lopez N. Cellular immune responses in amniotic fluid of women with preterm clinical chorioamnionitis. Inflamm Res. 2020 Feb;69(2):203-216. doi: 10.1007/s00011-019-01308-x. PMID: 31912179 Free PMC article.
14. Gomez-Lopez N, Romero R, Leng Y, Xu Y, Slutsky R, Levenson D, Pacora P, Jung E, Panaitescu B, Hsu CD. The origin of amniotic fluid monocytes/macrophages in women with intra-amniotic inflammation or infection. J Perinat Med. 2019 Oct 25;47(8):822-840. doi: 10.1515/jpm-2019-0262. PMID: 31494640 Free PMC article.

 

Education

 2019 - Microbiology/Bacteriology, University of Rochester

Advisor

Dr. Nardhy Gomez-Lopez

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