Position

PhD Candidate

Areas of interest

Elucidating the mechanisms of MEIG1 in mammalian spermiogenesis and fertilization

Publications

1. Niu C, Li T, Li W, Yap YT, Huang Q, Jiang L, Dhikhirullahi O, Miciuda A, Faddoul E, Song S, Griswold MD, Zhang Z. COPS5 is Essential for Sertoli Cell Function and Male Fertility in Mice. bioRxiv [Preprint]. 2025 Dec 22:2025.12.19.695357. doi: 10.64898/2025.12.19.695357. PMID: 41509289
2. Li T, Xu W, Yin L, Zhang J, DhikhirullahI O, Zhang Z, Yuan S.Effects of Aging on Mammalian Spermatogenesis From a Cellular Perspective. Mol Reprod Dev. 2025 Oct;92(10):e70061. doi: 10.1002/mrd.70061. PMID: 41054976
3. Dhikhirullahi O, Zhang Z. Male infertility. Syst Biol Reprod Med. 2025 Dec;71(1):416-438. doi: 10.1080/19396368.2025.2548492. Epub 2025 Sep 30. PMID: 41027459
4. Niu C, Dhikhirullahi O, Zhang Z. Preparation of Testicular Cells for Immunofluorescence Analysis of Manchette in Elongating Spermatids. Bio Protoc. 2025 Jun 20;15(12):e5340. doi: 10.21769/BioProtoc.5340. eCollection 2025 Jun 20. PMID: 40657541
5. Liu Y, Fang Y, Dhikhirullahi O, Zhang L, Zhang Z. Intraflagellar Transport (IFT) and Sperm Formation. Adv Exp Med Biol. 2025;1469:395-409. doi: 10.1007/978-3-031-82990-1_17. PMID: 40301266 Review.
6. Sheng Y, Yap YT, Li W, Dhikhirullahi O, Niu C, Rabbani M, Krawetz SA, Hammoud SS, Orwig KE, Zhang Z. Normal embryo development needs MEIG1-mediated sperm formation. FASEB J. 2025 Mar 15;39(5):e70426. doi: 10.1096/fj.202500109R. PMID: 40035530
7. Li W, Niu C, Yap YT, Li T, Zheng C, Goswami M, Kandiraju S, Dhikhirullahi O, Xu J, Zhang J, Kelly CV, Zhang Z. Two-directional trafficking of the IFT25 protein in the developing mouse sperm flagella. Biol Reprod. 2024 Nov 19:ioae171. doi: 10.1093/biolre/ioae171. PMID: 39561113

 

Education

 2019 B.S. in Physiology, University of Ilorin

Advisor

Zhibing Zhang, M.D., Ph.D.

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