School of Medicine

Wayne State University School of Medicine

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Ph.D. Candidate

5243 Scott Hall

 
Areas

Understanding the Molecular Structure and Composition of the Neuronal Porosome

Biography
 
Publications
  1. Lewis KT, Maddipati KR, Naik AR, Jena BP. (2017). Unique lipid chemistry of synaptic vesicle and synaptosome membrane revealed using mass spectrometry. ACS Chemical Neuroscience. (in press)
  2. Arachchige MP, Laha SS, Naik AR, Lewis KT, Naik R, Jena, BP.(2016) Functionalized nanoparticles enable tracking the rapid entry and release of doxorubicin in human pancreatic cancer cells. Micron. 2017 Jan;92:25-31. doi: 10.1016/j.micron.2016.10.005. PMID: 27846432
  3. Naik, AR., Kulkarni, S. P., Lewis, K. T., Taatjes, D. J., Jena, B. P. (2015) Functional reconstitution of the insulin-secreting porosome complex in live cells.Endocrinology. 2016 Jan;157(1):54-60. PMID: 26523491
  4. Naik AR, Lewis KT, Jena BP. (2015) The Neuronal Porosome Complex in Health and Disease. Exp. Biol. Med. (Maywood) Online First, published on August 11, 2015 as doi:10.1177/1535370215598400.
  5. Rajagopal A, Kulkarni S, Lewis KT, Chen X, Maarouf A, Kelly CV, Taatjes DJ, Jena BP. Proteome of the insulin-secreting Min6 cell porosome complex: Involvement of Hsp90 in its assembly and function. J Proteomics. 2014 Nov 20;114C:83-92. PMID: 25464371
  6. Lewis KT, Maddipati KR, Taatjes DJ, Jena BP. Neuronal porosome lipidome. J Cell Mol Med. 2014 Sep 16. PMID: 25224862
  7. Hou X, Lewis KT, Wu Q, Wang S, Chen X, Flack A, Mao G, Taatjes DJ, Sun F, Jena BP. Proteome of the porosome complex in human airway epithelia: interaction with the cystic fibrosis transmembrane conductance regulator (CFTR). J Proteomics. 2014 Jan 16;96:82-91. PMID: 24220302
  8. Kovari, L.C., Brunzelle, J.S., Lewis, KT, Cho, W.J., Lee, J-S., Taatjes, D.J., Jena, B.P. (2013) X-ray solution structure of the native neuronal porosome-synaptic vesicle complex: Implication in neurotransmitter release. Micron. 2014 Jan;56:37-43. PMID: 24176623
  9. Shah C, Antonucci JV, Wilkinson JB, Wallace M, Ghilezan M, Chen P, Lewis K, Mitchell C, Vicini F. Twelve-year clinical outcomes and patterns of failure with accelerated partial breast irradiation versus whole-breast irradiation: results of a matched-pair analysis. Radiother Oncol. 2011 Aug;100(2):210-4. Epub 2011 Apr 15. PMID: 21497927

 

Awards & Honors
  • Marion I. Barnhart Graduate Student Award (2014)
  • Elected Graduate Student Representative (2014-2015)

 

Advisor
Bhanu Jena, Ph.D.
Education

2012 - B.S. in Biology, Oakland University