Wayne State University

Warrior strong
Login
Search

School of Medicine

Physiology

Gunther Publications

  1. Marang C, Scott B, Chambers J, Gunther LK, Yengo CM, Debold EP. A mutation in switch I alters the load-dependent kinetics of myosin Va. Nat Commun. 2023 May 30;14(1):3137. doi: 10.1038/s41467-023-38535-0. PMID: 37253724
  2. Liu PJ, Gunther LK, Garone ME, Zhang C, Perez D, Bi-Karchin J, Pellenz CD, Chase SE, Presti MF, Plante EL, Martin CE, Lovric S, Yengo CM, Hildebrandt F, Krendel M. Steroid-Resistant Nephrotic Syndrome-Associated <i>MYO1E</i> Mutations Have Differential Effects on Myosin 1e Localization, Dynamics, and Activity. J Am Soc Nephrol. 2022 Nov;33(11):1989-2007. doi: 10.1681/ASN.2021111505. PMID: 36316095
  3. Gunther LK, Cirilo JA Jr, Desetty R, Yengo CM. Deafness mutation in the MYO3A motor domain impairs actin protrusion elongation mechanism. Mol Biol Cell. 2022 Jan 1;33(1):ar5. doi: 10.1091/mbc.E21-05-0232. PMID: 34788109
  4. Cirilo JA Jr, Gunther LK, Yengo CM. Functional Role of Class III Myosins in Hair Cells. Front Cell Dev Biol. 2021 Feb 25;9:643856. doi: 10.3389/fcell.2021.643856. eCollection 2021. PMID: 33718386 Free PMC article.
  5. Gunther LK, Rohde JA, Tang W, Cirilo JA Jr, Marang CP, Scott BD, Thomas DD, Debold EP, Yengo CM. FRET and optical trapping reveal mechanisms of actin activation of the power stroke and phosphate release in myosin V. J Biol Chem. 2020 Dec 18;295(51):17383-17397. doi: 10.1074/jbc.RA120.015632. PMID: 33453985
  6. Gunther LK, Rohde JA, Tang W, Walton SD, Unrath WC, Trivedi DV, Muretta JM, Thomas DD, Yengo CM  Converter domain mutations in myosin alter structural kinetics and motor function. J Biol Chem. 2019 Feb 1;294(5):1554-1567. doi: 10.1074/jbc.RA118.006128. PMID: 30518549
  7. Gunther LK, Yengo CM. Getting site-specific with actomyosin inhibitors. J Biol Chem. 2018 Aug 3;293(31):12299-12300. doi: 10.1074/jbc.H118.004679. PMID: 30076260
  8. Dantas VGL, Raval MH, Ballesteros A, Cui R, Gunther LK, Yamamoto GL, Alves LU, Bueno AS, Lezirovitz K, Pirana S, Mendes BCA, Yengo CM, Kachar B, Mingroni-Netto RC. Characterization of a novel MYO3A missense mutation associated with a dominant form of late onset hearing loss. Sci Rep. 2018 Jun 7;8(1):8706. doi: 10.1038/s41598-018-26818-2. PMID: 29880844
  9. Gunther LK, Feng HZ, Wei H, Raupp J, Jin JP, Sakamoto T. Effect of N-terminal extension of cardiac troponin I on the Ca2+ regulation of ATP-binding and ADP dissociation of myosin II in native cardiac myofibrils. Biochemistry 2016 Feb 10. PMID: 26862665; PMCID: PMC5278900
  10. Bao J, Wang S, Gunther LK, Kitajiri SI, Li C, Sakamoto T. The actin-bundling protein TRIOBP-4 and -5 promotes the motility of pancreatic cancer cells. Cancer Lett. 2014 Aug 15. PMID: 25130170
  11. Gunther LK, Furuta K, Bao J, Urbanowski MK, Kojima H, White HD, Sakamoto T. Coupling of two non-processive myosin 5c dimers enables processive stepping along actin filaments. Sci Rep. 2014 May 9;4:4907. PMID: 24809456; PMCID: PMC4014986
  12. Bao J, Huck D, Gunther LK, Sellers JR, Sakamoto T. Actin structure-dependent stepping of myosin 5a and 10 during processive movement. PLoS One. 2013 Sep 19;8(9):e74936. PMID: 24069366; PMCID: PMC3777900
  13. Bao J, Bielski E, Bachhawat A, Taha D, Gunther LK, Thirumurugan K, Kitajiri S, Sakamoto T. R1 motif is the major actin-binding domain of TRIOBP-4. Biochemistry. 2013 Aug 6;52(31):5256-64. PMID: 23789641