DCTP Sponsored Students

  • Kendall Case

    Ph.D. Candidate in Biological Sciences
    Mentor: Miriam Greenberg, Ph.D. & TBN
    Research: Regulation of inositol synthesis: Phosphoregulation of human and yeast MIPS

    Publications:

    1. Case KC, Salsaa M, Yu W, Greenberg ML. Regulation of Inositol Biosynthesis: Balancing Health and Pathophysiology. Handb Exp Pharmacol. 2020;259:221-260. doi: 10.1007/164_2018_181. PMID: 30591968
    2. Salsaa M, Case K, Greenberg ML. Orchestrating phospholipid biosynthesis: Phosphatidic acid conducts and Opi1p performs. J Biol Chem. 2017 Nov 10;292(45):18729-18730. doi: 10.1074/jbc.H117.809970. Review. PMID: 29127205..
  • Andrew Kulek

    MD/PhD Candidate in Biochemistry/Immunology
    Mentor: Karin Przyklenk, Ph.D.
    Research: The role of mitochondrial morphosis within the ischemic conditioning paradigm: an exploration of fission and fusion events during cardioprotection

    Publications:

    1. Kulek AR, Anzell A, Wider JM, Sanderson TH, Przyklenk K. Mitochondrial Quality Control: Role in Cardiac Models of Lethal Ischemia-Reperfusion Injury. Cells 2020, 9, 214; DOI: 10.3390/cells9010214
    2. Iraji A, Chen H, Wiseman N, Zhang T, Welch R, O'Neil B., Kulek A, Ayaz SI Wang X. Zuk C, Haacke EM, Liu T, Kou Z. Connectome-scale assessment of structural and functional connectiv-ity in mild traumatic brain injury at the acute stage. Neuroimage Clin (2016) 12:100-115.
    3. Iraji A, Benson RR, Welch RD, O'Neil BJ, Woodard JL, Ayaz SI, Kulek A, Medado, Soltanian-Zadeh H, Liu T, Haacke EM, Kuo Z. Resting State Functional Connectivity in Mild Traumatic Brain Injury at the Acute Stage. J Neurotrauma 2015;32(14): 1031-1045
    4. Ayaz SI, Thomas C, Kulek A. Tolomello R, Mika V, Robinson D, Medado P, Pearson C, Prichep L, O'Neil BJ. Comparison of Quantitative EEG to current clinical decision rules for Head CT use in acute mild traumatic brain injury in the ED. American Journal of Emergency Medicine 2015, 33(4):493-6.
    5. Guo J, Chen XF, Liu J, Lin HY, Han HW, Liu HC, Huang SC, Shahla BK, Kulek A, Qi JL, Wang XM, Ling LJ, Yang YH. Novel Shikonin Derivatives Targeting Tubulin as Anticancer Agents. Chemical Biology & Drug Design 2014; 84(5):603-15.
    6. Kou Z, Gattu R, Kobeissy F, Welch RD, O'Neil BJ, Woodard JL, Ayaz SI, Kulek A, Kas-Shamoun R, Mika V, Zuk C, Tomasello F, Mondello S. Combining Biochemical and Imaging Markers to Improve Diagnosis and Characterization of Mild Traumatic Brain Injury in the Acute Setting: Results from a Pilot Study. PLoS ONE 2013; 8(11): e80296
  • Peter Levanovich

    Ph.D. Candidate in Physiology
    Mentor: Noreen Rossi, M.D.
    Research: Fructose high-salt diet induces neuronal plasticity within the paraventricular nucleus and contributes to renal morbidity

    Publications:

    1. Levanovich PE, Diaczok A, Rossi NF. Clinical and Molecular Perspectives of Monogenic Hypertension. Curr Hypertens Rev. 2019 Apr 9. doi: 10.2174/1573402115666190409115330. PMID: 30963979
    2. Komnenov D, Levanovich PE, Rossi NF. Hypertension Associated with Fructose and High Salt: Renal and Sympathetic Mechanisms. Nutrients. 2019 Mar 7;11(3). pii: E569. doi: 10.3390/nu11030569. PMID: 30866441
    3. Rajaganapathy BR, Janicki JJ, Levanovich P, Tyagi P, Hafron J, Chancellor MB, Krueger S, Marples B. Intravesical Liposomal Tacrolimus Protects against Radiation Cystitis Induced by 3-Beam Targeted Bladder Radiation. J Urol. 2015 Aug;194(2):578-84. PMID: 25839382
    4. Levanovich PE, Diokno A, Hasenau DL, Lajiness M, Pruchnic R, Chancellor MB. Intradetrusor injection of adult muscle-derived cells for the treatment of underactive bladder: pilot study. Int Urol Nephrol. 2015 Mar;47(3):465-7. PMID: 25663053
    5. Smith PP, Tyagi P, Kuchel GA, Pore S, Chermansky C, Chancellor M, Yoshimura N, Levanovich P. Advanced therapeutic directions to treat the underactive bladder. Int Urol Nephrol. 2014 Sep;46 Suppl 1:S35-44. PMID: 25238893
  • Ph.D. Candidate in Pharmaceutical Sciences
    Mentor: Zhengping Yi, Ph.D.
    Research: Protein Phosphatase 2A in Metformin's Action in Primary Human Skeletal Muscle Cells

    Publications:

    1. Qi Y, Zhang X, Seyoum B, Msallaty Z, Mallisho A, Caruso M, Damacharla D, Ma D, Al-Janabi W, Tagett R, Alharbi M, Calme G, Mestareehi A, Draghici S, Abou-Samra A, Kowluru A, Yi Z. Kinome Profiling Reveals Abnormal Activity of Kinases in Skeletal Muscle From Adults With Obesity and Insulin Resistance. J Clin Endocrinol Metab. 2020 Mar 1;105(3). pii: dgz115. doi: 10.1210/clinem/dgz115. PMID: 31652310
    2. Damacharla D, Thamilselvan V, Zhang X, Mestareehi A, Yi Z, Kowluru A. Quantitative proteomics reveals novel interaction partners of Rac1 in pancreatic β-cells: Evidence for increased interaction with Rac1 under hyperglycemic conditions. Mol Cell Endocrinol. 2019 Aug 20;494:110489. doi: 10.1016/j.mce.2019.110489. PMID: 31202817

    Cameron Pinnock

  • PhD. Candidate in Biomedical Engineering
    Mentors:  Mai Lam, Ph.D. and JP Jin, M.D., Ph.D.
    Research: In Vitro Atherosclerosis Disease Model via the Ring Stacking Method

    Publications:

    1. Xi J, Li M, Jing B, An M, Yu C, Pinnock C, Zhu Y, Lam M, Liu H. Long-Circulating Amphiphilic Doxorubicin for Tumor Mitochondria-Specific Targeting. ACS Appl Mater Interfaces. 2018 Nov 27. doi: 10.1021/acsami.8b17399. PMID: 30479120
    2. Patel B, Xu Z, Pinnock CB, Kabbani LS, Lam MT. Self-assembled Collagen-Fibrin Hydrogel Reinforces Tissue Engineered Adventitia Vessels Seeded with Human Fibroblasts. Sci Rep. 2018 Feb 19;8(1):3294. doi: 10.1038/s41598-018-21681-7. PMID: 29459640 PMCID: PMC5818609
    3. Pinnock CB, Xu Z, Lam MT. Scaling of Engineered Vascular Grafts Using 3D Printed Guides and the Ring Stacking Method. J Vis Exp. 2017 Mar 27;(121). doi: 10.3791/55322. PMID: 28447994 Pinnock CB, Meier EM, Joshi NN, Wu B, Lam MT. Customizable engineered blood vessels using 3D printed inserts. Methods. 2016 Apr 15;99:20-7. doi: 10.1016/j.ymeth.2015.12.015. Epub 2015 Dec 28. PMID: 26732049

    PhD. Candidate in Physiology
    Mentors:  Robert Wessells, Ph.D.
    Research: Excitability and Plasticity of Octopaminergic Neurons During Chronic Exercise

    Publications:

    1. Richardson K, Wessells RJ. Commentary: Octopamine Drives Endurance Exercise Adaptations if Drosophila.  J Neurology & Neuromedicine 3(5):29-32 2018.